Abstract
The paper describes a case report of a patient with a significant history of opioid-induced dysfunction of the sphincter of Oddi, who required morphine sulfate to manage oral mucositis pain, and who was successfully treated with concomitant oral naloxegol (Moventig: Kyowa Kirin, Galashiels, UK).
Keywords:
analgesics, opioid; naloxegol; narcotic antagonists; sphincter of Oddi.
© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.
MeSH terms
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Administration, Oral
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Analgesics, Opioid / adverse effects*
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Carcinoma, Squamous Cell / complications
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Humans
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Male
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Middle Aged
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Morphinans / administration & dosage
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Morphinans / therapeutic use*
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Morphine / adverse effects*
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Mucositis / complications
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Mucositis / drug therapy
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Narcotic Antagonists / administration & dosage
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Narcotic Antagonists / therapeutic use*
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Pain / complications
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Pain / drug therapy
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Polyethylene Glycols / administration & dosage
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Polyethylene Glycols / therapeutic use*
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Spasm / chemically induced*
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Spasm / drug therapy*
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Sphincter of Oddi Dysfunction / chemically induced
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Sphincter of Oddi Dysfunction / drug therapy*
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Sphincter of Oddi Dysfunction / physiopathology
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Tonsillar Neoplasms / complications
Substances
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Analgesics, Opioid
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Morphinans
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Narcotic Antagonists
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Polyethylene Glycols
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naloxegol
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Morphine