Herpes zoster and meningitis in an immunocompetent child: a case report

J Med Case Rep. 2019 Jun 15;13(1):182. doi: 10.1186/s13256-019-2082-z.

Abstract

Background: Development of neurological complications of varicella zoster virus reactivation is relatively uncommon, particularly in an immunocompetent child.

Case presentation: An 11-year-old Asian girl presented with headache and skin rash on her left chest. She was diagnosed with meningitis, and herpes zoster was confirmed by polymerase chain reaction using cerebrospinal fluid. Acyclovir was administered intravenously. Given the favorable evolution of the clinical course, she was discharged from the hospital on day 8 of her illness. She had no apparent sequelae or comorbidities at the time of the 6-week follow-up.

Conclusions: Neurological complications such as meningitis due to varicella zoster virus reactivation are uncommon, especially in an immunocompetent child; no specific immune deficiency was identified in our patient. We conclude that, although rare, varicella zoster virus should be recognized as a potential cause of viral meningitis in immunocompetent children.

Keywords: Acyclovir; Herpes zoster; Immunocompetent child; Meningitis; Varicella zoster virus.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / administration & dosage*
  • Administration, Intravenous
  • Antiviral Agents
  • Cerebrospinal Fluid / virology*
  • Child
  • Exanthema / diagnosis
  • Exanthema / etiology
  • Female
  • Headache / diagnosis
  • Headache / etiology
  • Herpes Zoster* / complications
  • Herpes Zoster* / diagnosis
  • Herpes Zoster* / drug therapy
  • Herpes Zoster* / physiopathology
  • Herpesvirus 3, Human / isolation & purification*
  • Humans
  • Immunocompetence
  • Meningitis, Viral* / diagnosis
  • Meningitis, Viral* / drug therapy
  • Meningitis, Viral* / etiology
  • Meningitis, Viral* / physiopathology
  • Treatment Outcome

Substances

  • Antiviral Agents
  • Acyclovir