A study of the decrease of skin collagen content, skin thickness, and bone mass in the postmenopausal woman

Obstet Gynecol. 1987 Dec;70(6):840-5.

Abstract

The skin collagen content, skin thickness, metacarpal index, and forearm bone mineral content in postmenopausal women showed a similar decline of between 1-2% per year after the menopause. All four parameters showed a decline that was significant when compared with the years from the menopause. Significant correlations between all four parameters suggest that a similar pathology causes the decrease in bone mass and skin thickness--a decline in the connective tissue element that is common to both bone and skin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bone and Bones / analysis*
  • Collagen / analysis*
  • Female
  • Follicle Stimulating Hormone / blood
  • Humans
  • Hydroxyproline / analysis
  • Menopause*
  • Metacarpus / diagnostic imaging
  • Middle Aged
  • Radiography
  • Radionuclide Imaging
  • Skin / analysis*
  • Skin / anatomy & histology*
  • Skin / diagnostic imaging

Substances

  • Follicle Stimulating Hormone
  • Collagen
  • Hydroxyproline