Rotavirus vaccination has been associated with a short-term increased risk of intussusception. Our analysis of insurance claims for 1 858 827 US children with 544 recorded cases of intussusception found a nonsignificant decrease in intussusception (hazard ratio, 0.79 [95% confidence interval, 0.57-1.09]) in fully rotavirus-vaccinated children followed up to the age of 2 years.
Keywords: immunizations; intussusception; pediatric gastroenteritis; rotavirus; rotavirus vaccine.
Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society 2019.