Flecainide acetate is an oral class Ic antiarrhythmic drug (AAD) that blocks cardiac Na+ channels and received FDA approval in 1984. Flecainide is used in paroxysmal supraventricular tachycardia (PSVTs), including atrioventricular nodal re-entrant tachycardia (AVNRT), AV re-entrant tachycardia (AVRT), and atrial fibrillation/atrial flutter in patients who do not have structural heart disease. This activity will highlight the mechanism of action, pharmacodynamics, evidenced-based usage, and toxicity. Flecainide is predominantly used for atrial fibrillation and other supraventricular arrhythmias.
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