Clear Cell Acanthoma

Excerpt

Clear cell acanthoma (CCA), also known as “Degos acanthoma” and “acanthome cellules Claires of Degos and Civatte,” was first described by Degos et al. in 1962. It is a rare, benign tumor of unknown etiology. Although most commonly located on the lower extremities, clear cell acanthomas can also appear on the trunk, forearm, face, inguinal area, and few cases of nipple and areola lesions have been reported. Lesions are usually solitary; however, there are reports of rare cases of multiple disseminated clear cell acanthomas. These tumors clinically present in middle-aged to elderly individuals as an asymptomatic, slowly enlarging, red or red-brown, dome-shaped papule or nodule with a wafer-like scale collarette. Prognosis is excellent for these lesions as they are benign. Skin biopsy is usually performed to confirm the diagnosis, but a variety of other methods can also accomplish the removal.