Rare Pediatric Invasive Gliofibroma Has BRAFV600E Mutation and Transiently Responds to Targeted Therapy Before Progressive Clonal Evolution

Affiliations

• ¹ Division of Hematology, Oncology, and Blood and Marrow Transplant Program, Children's Center for Cancer and Blood Diseases, Department of Pediatrics, Children's Hospital Los Angeles.
• ² Department of Pathology, University of Southern California, Los Angeles, CA.
• ³ Department of Radiology, University of Southern California, Los Angeles, CA.
• ⁴ Division of Neurosurgery, Children's Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, CA.
• ⁵ Department of Pediatrics, University of Southern California, Los Angeles, CA.
• ⁶ Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA.