Aortogenic Embolic Stroke Diagnosed by a Pathological Examination of Endovascularly Removed Thrombus: An Autopsy Report

Intern Med. 2019 Oct 1;58(19):2851-2855. doi: 10.2169/internalmedicine.2857-19. Epub 2019 Jun 7.

Abstract

Complex aortic atheroma is a high-risk factor for recurrent embolic stroke. An accurate identification of stroke etiology is clinically important; however, it can be challenging. A 91-year-old man with atrial fibrillation was diagnosed with cardioembolic stroke and treated with mechanical thrombectomy. The removed thrombus microscopically contained foamy cells, suggesting an atheroembolism. An autopsy revealed an atherosclerotic lesion with ulceration, located in the aortic arch. At the lesion, the plaque had microscopically ruptured into the lumen. We therefore concluded that the aortic atherosclerotic lesion was the embolic source. Removed thrombi should be pathologically examined even if a cardioembolic stroke is clinically suspected.

Keywords: aortogenic embolic stroke; atherosclerosis; cerebral infarction; complex aortic atheroma; embolism; pathology.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Aortic Diseases / complications*
  • Aortic Diseases / diagnosis
  • Atrial Fibrillation / complications*
  • Autopsy
  • Cerebral Angiography
  • Embolism, Cholesterol / diagnosis*
  • Embolism, Cholesterol / etiology
  • Embolism, Cholesterol / surgery
  • Endovascular Procedures / methods
  • Fatal Outcome
  • Humans
  • Intracranial Embolism / diagnosis*
  • Intracranial Embolism / etiology
  • Intracranial Embolism / surgery
  • Magnetic Resonance Imaging
  • Male
  • Plaque, Atherosclerotic / complications*
  • Plaque, Atherosclerotic / diagnosis