A survey of the anesthetic management of pediatric kidney transplantation in France

Pediatr Transplant. 2019 Sep;23(6):e13509. doi: 10.1111/petr.13509. Epub 2019 Jun 5.

Abstract

Background: Renal transplantation is the best available therapeutic option for end-stage renal failure in both children and adults. However, little is known about anesthetic practice during pediatric renal transplantation.

Material and methods: The study consisted of a national survey about anesthetic practice during pediatric renal transplantation in France. French tertiary pediatric centers performing renal transplants were targeted, and one physician from each team was asked to complete the survey. The survey included patient data, preoperative assessment and optimization data, and intraoperative anesthesia data (drugs, ventilation, and hemodynamic interventions).

Results: Twenty centers performing kidney transplantation were identified and contacted to complete the survey, and eight responded. Surveyed centers performed 96 of the 122 pediatric kidney transplantations performed in France in 2017 (79%). Centers consistently performed echocardiography and ultrasound examinations of the great veins preoperatively and consistently employed esophageal Doppler cardiac output estimation and vasopressors intraoperatively. All other practices were found to be heterogeneous. Central venous pressure was monitored in six centers, and dopamine was administered perioperatively in two centers.

Conclusions: The current study provides a snapshot of the perioperative management of pediatric kidney transplantation in France. Results emphasize the need for both standardization of practice and awareness of recent evidence against the use of CVP monitoring and dopamine infusions.

Keywords: children; kidney; national survey; transplantation.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Anesthesia / methods*
  • Anesthetics / therapeutic use*
  • Child
  • Child, Preschool
  • Dopamine / therapeutic use
  • Echocardiography
  • Esophagus
  • France
  • Hemodynamics
  • Humans
  • Infant
  • Infant, Newborn
  • Kidney / blood supply*
  • Kidney Diseases / surgery*
  • Kidney Transplantation*
  • Monitoring, Intraoperative / methods
  • Surveys and Questionnaires
  • Ultrasonography
  • Ultrasonography, Doppler

Substances

  • Anesthetics
  • Dopamine