The growth and laser amplifier performance of a large-aperture Nd:LuAG ceramic are reported. Using the vacuum sintering and high-temperature insostatic pressing (HIP) methods, three pieces of a 50 mm-aperture Nd:LuAG ceramic are fabricated and used as the gain medium in a diode-pumped nanosecond distributed active mirror amplifier chain (DAMAC). The energy storage capacity of large-aperture Nd:LuAG is investigated and compared with that of Nd:YAG. Energy amplification up to 10.3 J at 10 Hz is achieved, which, to the best of our knowledge, produces the highest peak power (1 GW) using Nd:LuAG. The excellent energy storage and extraction performance confirm the great potential of Nd:LuAG in high-energy scaling.