Progressive sixth nerve palsy secondary to intracavernous arachnoid cyst and complicated by contralateral optic nerve sheath meningioma

Eur J Ophthalmol. 2020 Sep;30(5):NP86-NP89. doi: 10.1177/1120672119853133. Epub 2019 Jun 3.

Abstract

Introduction: Optic nerve sheath meningiomas and intracavernous arachnoid cysts are both fairly rare conditions, and to the best of our knowledge, have not been previously reported to co-occur in the same patient. Both can cause diplopia, but only ONSMs have been documented to demonstrate progressive worsening of ocular motility.

Case report: A 67-year-old woman with blur and diplopia demonstrated a right optic neuropathy and limited ductions bilaterally. Neuroimaging revealed a right optic nerve sheath meningioma and left intracavernous arachnoid cyst. She was conservatively managed with neurosurgical surveillance for 1.5 years, until her diplopia worsened. Ocular motility re-evaluation demonstrated a worsening left abduction deficit, suggesting interval change of the intracavernous cyst, rather than the meningioma.

Conclusion: There are only a few reported cases of cranial nerve VI palsy secondary to a cavernous sinus arachnoid cyst. However, this is the first reported case in a patient with a concurrent optic nerve sheath meningioma, and the first case demonstrating progressive worsening of a sixth cranial nerve palsy from an intracavernous arachnoid cyst. Determining which comorbidity caused worsening of symptoms played a critical role in the management of this patient.

Keywords: Arachnoid cyst; cavernous sinus; diplopia; optic nerve sheath meningioma; optic neuropathy; sixth cranial nerve palsy.

Publication types

  • Case Reports

MeSH terms

  • Abducens Nerve Diseases / diagnosis
  • Abducens Nerve Diseases / etiology*
  • Aged
  • Arachnoid Cysts / complications*
  • Arachnoid Cysts / diagnostic imaging
  • Cavernous Sinus / diagnostic imaging
  • Cavernous Sinus / pathology*
  • Diplopia / etiology
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Meningioma / complications*
  • Meningioma / diagnostic imaging
  • Optic Nerve Neoplasms / complications*
  • Optic Nerve Neoplasms / diagnostic imaging
  • Vision Disorders / etiology