Metachronous multiple thymoma with different clinical behavior and pathological findings

Tomonari Oki; Toru Nakamura; Yoshifumi Arai; Yoshiro Otsuki; Futoru Toyoda

doi:10.1007/s13691-016-0249-7

Metachronous multiple thymoma with different clinical behavior and pathological findings

Int Cancer Conf J. 2016 Apr 16;5(3):158-161. doi: 10.1007/s13691-016-0249-7. eCollection 2016 Jul.

Authors

Tomonari Oki¹, Toru Nakamura¹, Yoshifumi Arai², Yoshiro Otsuki², Futoru Toyoda¹

Affiliations

¹ 1Department of General Thoracic Surgery, Seirei Hamamatsu General Hospital, Sumiyoshi 2-12-12, Naka-ku, Hamamatsu, Shizuoka 430-8558 Japan.
² 2Department of Pathology, Seirei Hamamatsu General Hospital, Sumiyoshi 2-12-12, Naka-ku, Hamamatsu, Shizuoka 430-8558 Japan.

Abstract

A 70-year-old woman presented with a nodule in the left hilum on a chest radiograph 3 years before. Another mass emerged caudal to the initial nodule and was diagnosed as thymoma. A surgical specimen revealed two components: an encapsulated rostral nodule and a caudal mass invading the left lung. Histological findings showed that the rostral nodule was a stage 1 type B2 thymoma, whereas the caudal mass was a stage 3 type B3 thymoma. Based on the differences in biological behavior and histological findings, we concluded that these tumors derived from multicentric origin.

Keywords: Metachronous; Multicentric; Multiple; Thymoma.

Publication types

Case Reports