Genome-wide analysis of DNA replication timing in single cells: Yes! We're all individuals

Anne D Donaldson; Conrad A Nieduszynski

doi:10.1186/s13059-019-1719-y

Genome-wide analysis of DNA replication timing in single cells: Yes! We're all individuals

Genome Biol. 2019 May 30;20(1):111. doi: 10.1186/s13059-019-1719-y.

Authors

Anne D Donaldson¹, Conrad A Nieduszynski²

Affiliations

¹ Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK. a.d.donaldson@abdn.ac.uk.
² Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.

Abstract

Recent studies have accomplished the extraordinary feat of measuring the exact status of DNA replication in individual cells. We outline how these studies have revealed surprising uniformity in how cells replicate their DNA, and consider the implications of this remarkable technological advance.

Genome-wide analysis of DNA replication timing in single cells: Yes! We're all individuals

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Abstract

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