Heterozygous Spink1 c.194+2T>C mutant mice spontaneously develop chronic pancreatitis

Gut. 2020 May;69(5):967-968. doi: 10.1136/gutjnl-2019-318790. Epub 2019 May 29.

Authors

Chang Sun^#^{1

2}, Muyun Liu^#^{1

3}, Wei An^#¹, Xiaotong Mao¹, Hui Jiang⁴, WenBin Zou^{1

2}, Hao Wu¹, Zhuan Liao^{1

2}, Zhaoshen Li^{1

2}

Affiliations

¹ Department of Gastroenterology, Changhai Hospital, the Second Military Medical University/Naval Medical University, Shanghai, China.
² Shanghai Institute of Pancreatic Diseases, Shanghai, China.
³ Department of Gastroenterology, Navy 905 Hospital, the Second Military Medical University/Naval Medical University, Shanghai, China.
⁴ Department of Pathology, Changhai Hospital, the Second Military Medical University/Naval Medical University, Shanghai, China.

^# Contributed equally.

PMID: 31142585
DOI: 10.1136/gutjnl-2019-318790

No abstract available

Keywords: chronic pancreatitis; gene mutation.

Publication types

Letter
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Heterozygote
Humans
Mice
Mutation
Pancreatitis, Chronic*
Trypsin Inhibitor, Kazal Pancreatic*

Substances

SPINK1 protein, human
Trypsin Inhibitor, Kazal Pancreatic