Performance of HAS-BLED and CRUSADE risk scores for the prediction of haemorrhagic events in patients with stable coronary artery disease

Cardiovasc J Afr. 2019;30(4):198-202. doi: 10.5830/CVJA-2019-014. Epub 2019 Mar 29.

Abstract

We aimed to compare the power of the HAS-BLED and CRUSADE risk scores in predicting in-hospital bleeding events in patients with stable coronary artery disease undergoing elective coronary angiography. A total of 405 consecutive patients were included in the study. The mean HAS-BLED score was significantly higher (p < 0.001) in the in-hospital bleeding group. In patients with a HAS-BLED score ≥ 3, the in-hospital bleeding rate was significantly higher than in those with a HAS-BLED score < 3 (p < 0.001). Receiver operating characteristic curve analysis revealed that the HAS-BLED score was superior in predicting in-hospital bleeding events compared to the CRUSADE score [area under the curve (AUC) = 0.684 vs 0.569, respectively, p = 0.002]. Also in the percutaneous coronary intervention subgroup, the HAS-BLED score was superior to the CRUSADE score (AUC = 0.722 vs 0.520, respectively, p = 0.002). We showed that the HAS-BLED and CRUDASE scores are helpful in stable patients undergoing elective coronary angiography. Our results suggest that as a practical, easy-to-implement and more predictive scoring system, the HAS-BLED score was more useful for predicting in-hospital bleeding in patients who did not present with acute coronary syndrome.

Keywords: coronary artery disease; angiography; haemorrhage.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Coronary Angiography / adverse effects*
  • Coronary Artery Disease / complications
  • Coronary Artery Disease / diagnostic imaging*
  • Coronary Artery Disease / therapy
  • Decision Support Techniques*
  • Female
  • Hemorrhage / etiology*
  • Humans
  • Inpatients
  • Male
  • Middle Aged
  • Percutaneous Coronary Intervention / adverse effects
  • Predictive Value of Tests
  • Prognosis
  • Risk Assessment
  • Risk Factors