Analytical Solution of the Time-Dependent Microfluidic Poiseuille Flow in Rectangular Channel Cross-Sections and its Numerical Implementation in Microsoft Excel

Biosensors (Basel). 2019 May 24;9(2):67. doi: 10.3390/bios9020067.

Abstract

We recently demonstrated that the Navier-Stokes equation for pressure-driven laminar (Poiseuille) flow can be solved in any channel cross-section using a finite difference scheme implemented in a spreadsheet analysis tool such as Microsoft Excel. We also showed that implementing different boundary conditions (slip, no-slip) is straight-forward. The results obtained in such calculations only deviated by a few percent from the (exact) analytical solution. In this paper we demonstrate that these approaches extend to cases where time-dependency is of importance, e.g., during initiation or after removal of the driving pressure. As will be shown, the developed spread-sheet can be used conveniently for almost any cross-section for which analytical solutions are close-to-impossible to obtain. We believe that providing researchers with convenient tools to derive solutions to complex flow problems in a fast and intuitive way will significantly enhance the understanding of the flow conditions as well as mass and heat transfer kinetics in microfluidic systems.

Keywords: Microsoft Excel; Navier–Stokes; Poiseuille flow; dynamic flow; finite difference method; initiation of flow; microfluidics; numerical techniques; time dependent flow.

MeSH terms

  • Microfluidics / methods*
  • Models, Theoretical
  • Software