[Musculoskeletal Manifestation in Inflammatory Bowel Disease]

Korean J Gastroenterol. 2019 May 25;73(5):276-284. doi: 10.4166/kjg.2019.73.5.276.
[Article in Korean]

Abstract

Almost 50% of patients with inflammatory bowel disease (IBD) exhibit at least one extra-intestinal manifestation in their lifetime. Extra-intestinal manifestations of IBD are often associated with the intestinal disease activity, reducing the quality of life of the patient but rarely leading to fatal complications. Musculoskeletal involvement is the most frequent extra-intestinal manifestation of patients with IBD but this rarely occurs before IBD is diagnosed. They are manifested in various forms, such as arthropathy, fibromyalgia, and osteoporosis. Therefore, a multidisciplinary team approach including gastroenterologists and rheumatologists are necessary for optimal treatment. This review focuses on the diagnosis and treatment of musculoskeletal manifestations of IBD from the perspectives of rheumatologists who can assist gastroenterologists.

Keywords: Inflammatory bowel diseases; Joint diseases; Musculoskeletal diseases.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Antidepressive Agents / therapeutic use
  • Arthritis / complications
  • Arthritis / drug therapy
  • Arthritis / pathology
  • Fibromyalgia / complications
  • Fibromyalgia / drug therapy
  • Fibromyalgia / pathology
  • Humans
  • Inflammatory Bowel Diseases / complications
  • Inflammatory Bowel Diseases / pathology*
  • Musculoskeletal Diseases / complications
  • Musculoskeletal Diseases / pathology*
  • Osteoporosis / complications
  • Osteoporosis / pathology
  • Sacroiliitis / complications
  • Sacroiliitis / pathology
  • Spondylitis / complications
  • Spondylitis / pathology

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antidepressive Agents