Low-friction and hydrophilic surfaces have critical applications in biomedical devices and implants. Existing methods to achieve such surfaces, for example, grafting polymer brushes, usually suffer from tedious steps and harsh reaction conditions, which limit practical applications. In this work, we propose a set of versatile ultralow-friction coatings applicable for diverse biomaterial surfaces via a one-step simple codeposition strategy with dopamine and hydrophilic monomers. The polymer coatings show ultralow-friction performance together with hydrophilic feature and antifouling property. The coefficient of friction of the as-prepared coating can be as low as 0.003 in pure water. The coating also provides superior and stable lubrication in biological fluids due to antifouling capability. Furthermore, the versatility of this strategy allows fabrication of multiple lubricious polymer coatings with different hydrophilic monomers and on diverse material surfaces. The typical application of this low-friction coating on a medical catheter was further demonstrated, which dramatically improved surface wettability and reduced friction of the outer surface of the catheter. In view of the versatility and remarkable lubrication ability, the multifunctional coatings may find important applications in biomedical devices and implants.