18 F-FDG PET/CT imaging: A supplementary understanding of pulmonary sclerosing pneumocytoma

Abstract

Background: We sought to investigate the clinical features and ¹⁸ F-FDG PET/CT characteristics of pulmonary sclerosing pneumocytoma (PSP).

Methods: We retrospectively reviewed and comparatively analyzed ¹⁸ F-FDG PET/CT imaging results of 22 patients with diagnosed PSP in our hospital from November 2009 to September 2015.

Results: The SUV_max in tumors was positively correlated with tumor size in typical PSPs (R = 0.806, R² = 0.650, P = 0.001); however, the SUV_max in tumors had no significant correlation with tumor size of atypical PSPs (R = 0.479, R² = 0.229, P = 0.162), and the degree of correlation between them attenuated when atypical PSPs were included (R = 0.518, R² = 0.268, P = 0.011). A majority (90%) of atypical PSPs were found in males. Symptomatic patients showed a higher SUV_max than the asymptomatic group (5.68 ± 3.63 vs. 2.76 ± 1.18, respectively, P = 0.002).

Conclusion: Tumor size and clinical features may be associated with increased FDG uptake in PSPs. Morphological differences may affect the correlation between tumor size and SUV_max in PSPs. The atypical form of PSP may be more common in men.

Keywords: 18Fluorine 2-fluoro-2-deoxy-d-glucose; positron emission tomography and computed tomography; pulmonary sclerosing pneumocytoma.