Esophagogastric Neoplasms Following Bariatric Surgery: an Updated Systematic Review

Obes Surg. 2019 Aug;29(8):2660-2669. doi: 10.1007/s11695-019-03951-z.

Abstract

The risk of gastric and/or esophageal cancers after bariatric surgery has been previously discussed in literature. A systematic review was performed to identify articles published between June 2012 and December 2018 reporting new cases of esophageal or gastric cancer not included in previous systematic reviews. Ten gastric malignancies, 28 esophageal cancers, and 2 gastro-intestinal stromal tumors (GIST) were identified. Primary bariatric surgery was a restrictive procedure in 26 cases, a purely malabsorptive procedure in 1 subject, and a gastric bypass in 13 patients. Although the vast majority of bariatric procedures seem to present a negligible relationship with any esophagogastric (EG) malignancy, published data remain incomplete. It was however considered of interest to update the number of EG neoplasms arisen following bariatric surgery.

Keywords: Bariatric surgery; Esophageal cancer; Gastric cancer; Mini-bypass; One-anastomosis gastric bypass.

Publication types

  • Systematic Review

MeSH terms

  • Bariatric Surgery / adverse effects*
  • Bariatric Surgery / methods
  • Bariatric Surgery / statistics & numerical data
  • Esophageal Neoplasms / epidemiology
  • Esophageal Neoplasms / etiology*
  • Gastric Bypass / adverse effects
  • Gastric Bypass / methods
  • Gastric Bypass / statistics & numerical data
  • Gastrointestinal Stromal Tumors / epidemiology
  • Gastrointestinal Stromal Tumors / etiology
  • Humans
  • Obesity, Morbid / epidemiology
  • Obesity, Morbid / surgery*
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Stomach Neoplasms / epidemiology
  • Stomach Neoplasms / etiology*