A simple platform with moving drops for downscaling chemical analysis incorporating smartphone detection

Sutasinee Apichai; Kajorngai Thajee; Wasin Wongwilai; Sunanta Wangkarn; Pathinan Paengnakorn; Chalermpong Saenjum; Kate Grudpan

doi:10.1016/j.talanta.2019.04.014

A simple platform with moving drops for downscaling chemical analysis incorporating smartphone detection

Talanta. 2019 Aug 15:201:226-229. doi: 10.1016/j.talanta.2019.04.014. Epub 2019 Apr 10.

Authors

Sutasinee Apichai¹, Kajorngai Thajee¹, Wasin Wongwilai², Sunanta Wangkarn¹, Pathinan Paengnakorn³, Chalermpong Saenjum⁴, Kate Grudpan⁵

Affiliations

¹ Center of Excellence for Innovation in Analytical Science and Technology, Chiang Mai University, Chiang Mai, 50200, Thailand; Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.
² Center of Excellence for Innovation in Analytical Science and Technology, Chiang Mai University, Chiang Mai, 50200, Thailand; Science and Technology Research Institute, Chiang Mai University, Chiang Mai, 50200, Thailand.
³ Center of Excellence for Innovation in Analytical Science and Technology, Chiang Mai University, Chiang Mai, 50200, Thailand; Biomedical Engineering Institute, Chiang Mai University, Chiang Mai, 50200, Thailand.
⁴ Center of Excellence for Innovation in Analytical Science and Technology, Chiang Mai University, Chiang Mai, 50200, Thailand; Department of Pharmaceutical Science, Faculty of Pharmacy, Chiang Mai, 50200, Thailand.
⁵ Center of Excellence for Innovation in Analytical Science and Technology, Chiang Mai University, Chiang Mai, 50200, Thailand; Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand; Science and Technology Research Institute, Chiang Mai University, Chiang Mai, 50200, Thailand. Electronic address: kgrudpan@gmail.com.

PMID: 31122415
DOI: 10.1016/j.talanta.2019.04.014

Abstract

A simple cost-effective device for downscaling chemical analysis with microliter-scale dropwise handing and smartphone detection is proposed. The platform was made from easily available materials. Drops of constant volume of analyte and reagent were placed onto a channel then moved by gravity force to mix and react with each other. The color change due to reaction was monitored with a smartphone. Assays of iron, copper and phosphate employing the platform were demonstrated with 1,10-phenanthroline, bicinchoninic acid and molybdate reagents, respectively. Kinetic study was also demonstrated for this simple device.

Keywords: Copper; Downscaling chemical analysis; Iron; Kinetic study; Micro moving drop; Phosphate; Platform; Smartphone.