Immunohistochemical validation studies in effusion cytology: A cautionary tale

Cancer Cytopathol. 2019 Nov;127(11):680-683. doi: 10.1002/cncy.22149. Epub 2019 May 22.
No abstract available

Keywords: alcohol-fixed; cell block; cytology; effusion; immunohistochemistry; validation.

MeSH terms

  • Antibodies, Monoclonal
  • Antibody Specificity
  • B7-H1 Antigen / analysis
  • Biomarkers, Tumor / analysis*
  • Body Fluids / chemistry*
  • Breast Neoplasms / chemistry*
  • Breast Neoplasms / diagnosis
  • Cyclin-Dependent Kinase Inhibitor p16 / analysis
  • Female
  • Histocytological Preparation Techniques*
  • Humans
  • Immunohistochemistry / methods*
  • Lung Neoplasms / chemistry
  • Lung Neoplasms / pathology
  • Mesothelioma / chemistry
  • Mesothelioma / pathology
  • Mesothelioma, Malignant
  • Practice Guidelines as Topic
  • Receptor, ErbB-2 / analysis
  • Receptors, Estrogen / analysis
  • Receptors, Progesterone / analysis
  • Sensitivity and Specificity
  • Ubiquitin-Protein Ligases / analysis
  • Validation Studies as Topic

Substances

  • Antibodies, Monoclonal
  • B7-H1 Antigen
  • Biomarkers, Tumor
  • CD274 protein, human
  • CDKN2A protein, human
  • Cyclin-Dependent Kinase Inhibitor p16
  • Receptors, Estrogen
  • Receptors, Progesterone
  • BRAP protein, human
  • Ubiquitin-Protein Ligases
  • ERBB2 protein, human
  • Receptor, ErbB-2