Introduction to Bioinformatics

Methods Mol Biol. 2019:1986:1-15. doi: 10.1007/978-1-4939-9442-7_1.

Abstract

How the scientific community looks at molecular biology today is very different from that 50 years ago. During this time technological developments have led to many significant findings that have shook one of the most important foundations of molecular biology: the central dogma. In this chapter, we will mention how these changes occurred and gave birth to a very important field of today's science, bioinformatics. We will also mention briefly the newest topics of molecular biology regarding bioinformatics technologies and skills.

Keywords: Bioinformatics; High-throughput technology; Molecular biology.

Publication types

  • Review

MeSH terms

  • Computational Biology / methods*
  • DNA Methylation / genetics
  • Epigenesis, Genetic
  • Histones / metabolism
  • RNA / genetics
  • Transcriptome / genetics

Substances

  • Histones
  • RNA