Identification of clonal complexes of Mycobacterium bovis in Brazil

Arch Microbiol. 2019 Oct;201(8):1047-1051. doi: 10.1007/s00203-019-01674-4. Epub 2019 May 20.

Abstract

Bovine tuberculosis is a disease that is widely distributed around the world. Its causative agent, Mycobacterium bovis, has characteristics of a microorganism with clonal multiplication in populations with no evidence of genetic exchange between strains, and, consequently, a group of strains can be identified as descending from a common ancestor. The aim of this study was to investigate the clonal complexes of M. bovis isolated from samples of lesions suggestive of bovine tuberculosis collected from slaughterhouses in various states of Brazil between 2006 and 2012. Ninety samples were analyzed, and it was found that 14.4% belonged to the clonal complex European1 and 81.1% to the clonal complex European2, while 4.65% were not identified as any of the four known complexes.

Keywords: Bovine tuberculosis; Clonal complex; Epidemiology; Mycobacterium bovis.

MeSH terms

  • Animals
  • Brazil / epidemiology
  • Cattle
  • Clonal Evolution / genetics
  • Mycobacterium bovis / classification*
  • Mycobacterium bovis / genetics*
  • Mycobacterium bovis / isolation & purification
  • Tuberculosis, Bovine / epidemiology*
  • Tuberculosis, Bovine / microbiology