Crystal structure of 4-(2-hy-droxy-3-meth-oxy-benzyl-amino)-benzoic acid di-methyl-formamide monosolvate monohydrate

Md Serajul Haque Faizi; Saima Kamaal; Arif Ali; Musheer Ahmad; Irina A Golenya

doi:10.1107/S2056989019005103

Crystal structure of 4-(2-hy-droxy-3-meth-oxy-benzyl-amino)-benzoic acid di-methyl-formamide monosolvate monohydrate

Acta Crystallogr E Crystallogr Commun. 2019 Apr 18;75(Pt 5):646-649. doi: 10.1107/S2056989019005103. eCollection 2019 May 1.

Authors

Md Serajul Haque Faizi¹, Saima Kamaal², Arif Ali², Musheer Ahmad², Irina A Golenya³

Affiliations

¹ Department of Chemistry, Langat Singh College, B. R. A. Bihar University, Muzaffarpur, Bihar, 842001, India.
² Department of Applied Chemistry, Faculty of Engineering & Technology, Aligarh, Muslim University, Aligarh, UP 202002, India.
³ National Taras Shevchenko University, Department of Chemistry, Volodymyrska, str., 64, 01601, Kyiv, Ukraine.

Abstract

The title compound, C₁₅H₁₅NO₄·C₃H₇NO·H₂O, a secondary amine mol-ecule, is accompanied by one equivalent of water and one equivalent of di-methyl-formamide (DMF) as solvents. The mol-ecule is non-planar, with a C_ar-yl-CH₂-NH-C_ar-yl torsion angle of -66.3 (3)°. In the crystal, O-H⋯O and N-H⋯O hydrogen-bonding inter-actions between the amine mol-ecules and the two types of solvent mol-ecule result in the formation of a layered structure extending parallel to (010).

Keywords: 2-hydroxy-3-methoxy-benzaldehyde; 4-aminobenzoic acid (PABA); crystal structure; dimethylformamide solvate; hydrogen bonding; secondary amine; vanillin derivative.

Grants and funding

This work was funded by UGC grant .