Paraneoplastic phenomenon in mesothelioma

Thorax. 2019 Jul;74(7):719-720. doi: 10.1136/thoraxjnl-2019-213176. Epub 2019 May 20.

Abstract

A 71-year-old man presented with breathlessness and visual disturbance. On examination of the chest, he had signs suggestive of a right-sided pleural effusion and a neurological examination yielded conjugate vertical gaze palsy. Subsequent investigations revealed pleural thickening and mesothelioma. His anti-Ma2 antibodies were positive indicating a paraneoplastic syndrome as the cause of the vertical gaze palsy.

Keywords: asbestos induced lung disease; lung cancer; mesothelioma; rare lung diseases.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Aged
  • Biopsy
  • Humans
  • Lung Neoplasms / complications*
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology
  • Male
  • Mesothelioma / complications*
  • Mesothelioma / diagnostic imaging
  • Mesothelioma / pathology
  • Mesothelioma, Malignant
  • Ophthalmoplegia / etiology*
  • Paraneoplastic Syndromes, Ocular / etiology*
  • Pleural Effusion, Malignant / etiology
  • Tomography, X-Ray Computed