Association of 32-bp deletion polymorphism and promoter methylation of PTEN and hepatitis C virus induced hepatocellular carcinoma

Br J Biomed Sci. 2019 Oct;76(4):195-197. doi: 10.1080/09674845.2019.1620475. Epub 2019 Jun 21.
No abstract available

Keywords: 32-bp deletion; HCC; HCV; PTEN; promoter methylation.

MeSH terms

  • Adult
  • Alleles
  • Carcinoma, Hepatocellular / etiology
  • Carcinoma, Hepatocellular / genetics*
  • Carcinoma, Hepatocellular / pathology
  • Case-Control Studies
  • DNA Methylation
  • Epigenesis, Genetic
  • Female
  • Gene Frequency
  • Genotype
  • Hepacivirus / growth & development
  • Hepacivirus / pathogenicity
  • Hepatitis C, Chronic / complications
  • Hepatitis C, Chronic / genetics*
  • Hepatitis C, Chronic / pathology
  • Humans
  • INDEL Mutation*
  • Liver Neoplasms / etiology
  • Liver Neoplasms / genetics*
  • Liver Neoplasms / pathology
  • Male
  • Middle Aged
  • Models, Genetic
  • PTEN Phosphohydrolase / genetics*
  • Promoter Regions, Genetic*

Substances

  • PTEN Phosphohydrolase
  • PTEN protein, human