Association between duration of excessive weight and arterial stiffness in middle-aged and older adults

Clin Exp Hypertens. 2020;42(3):213-217. doi: 10.1080/10641963.2019.1619752. Epub 2019 May 20.

Abstract

This study aims to evaluate the association between duration of overweight/obesity and arterial stiffness. In total, 103 men and women aged 45-68 years with a body mass index (BMI) of ≥25 kg/m2 were enrolled in this study. Duration of overweight/obesity was calculated for individuals with at least two consecutive BMI occurrences of ≥25 kg/m2 in the previous (5-year intervals from 20 years old) and present BMI information. Multiple regression analysis showed that carotid-femoral pulse wave velocity, an index of arterial stiffness, was independently associated with the duration of overweight/obesity, but not with current degree of overweight/obesity.

Keywords: Obesity period; aortic stiffness; cardiovascular risk.

MeSH terms

  • Aged
  • Body Mass Index
  • Cardiovascular Diseases* / epidemiology
  • Cardiovascular Diseases* / prevention & control
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obesity* / diagnosis
  • Obesity* / physiopathology
  • Overweight* / diagnosis
  • Overweight* / physiopathology
  • Pulse Wave Analysis
  • Risk Assessment
  • Risk Factors
  • Time Factors
  • Vascular Stiffness*