Microcontroller Implementation of Support Vector Machine for Detecting Blood Glucose Levels Using Breath Volatile Organic Compounds

Sensors (Basel). 2019 May 17;19(10):2283. doi: 10.3390/s19102283.

Abstract

This paper presents an embedded system-based solution for sensor arrays to estimate blood glucose levels from volatile organic compounds (VOCs) in a patient's breath. Support vector machine (SVM) was trained on a general-purpose computer using an existing SVM library. A training model, optimized to achieve the most accurate results, was implemented in a microcontroller with an ATMega microprocessor. Training and testing was conducted using artificial breath that mimics known VOC footprints of high and low blood glucose levels. The embedded solution was able to correctly categorize the corresponding glucose levels of the artificial breath samples with 97.1% accuracy. The presented results make a significant contribution toward the development of a portable device for detecting blood glucose levels from a patient's breath.

Keywords: breath disease detection; breath volatile organic compounds; diabetes; microcontroller implementation of SVM; support vector machine.

MeSH terms

  • Biosensing Techniques*
  • Blood Glucose / isolation & purification*
  • Breath Tests
  • Diabetes Mellitus / blood*
  • Diabetes Mellitus / pathology
  • Gas Chromatography-Mass Spectrometry
  • Humans
  • Hypoglycemia / blood
  • Hypoglycemia / pathology
  • Support Vector Machine
  • Volatile Organic Compounds / chemistry
  • Volatile Organic Compounds / isolation & purification*

Substances

  • Blood Glucose
  • Volatile Organic Compounds