Abstract
During the 2008-2012 pertussis epidemic in Australia, pertactin (Prn)-negative Bordetella pertussis emerged. We analyzed 78 isolates from the 2013-2017 epidemic and documented continued expansion of Prn-negative ptxP3 B. pertussis strains. We also detected a filamentous hemagglutinin-negative and Prn-negative B. pertussis isolate.
Keywords:
Australia; Bordetella pertussis; Fha-negative; Pertactin; Prn-negative; acellular vaccine; bacteria; filamentous haemagglutinin; fim2; pertussis; ptxP3.
Publication types
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Historical Article
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Research Support, Non-U.S. Gov't
MeSH terms
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Adhesins, Bacterial / genetics*
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Adhesins, Bacterial / immunology
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Alleles
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Australia / epidemiology
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Bacterial Outer Membrane Proteins / genetics*
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Bacterial Outer Membrane Proteins / immunology
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Bordetella pertussis / classification
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Bordetella pertussis / genetics*
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Bordetella pertussis / immunology
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History, 21st Century
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Humans
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Pertussis Vaccine / administration & dosage
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Pertussis Vaccine / immunology
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Phylogeny
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Virulence Factors, Bordetella / genetics*
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Virulence Factors, Bordetella / immunology
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Whooping Cough / epidemiology*
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Whooping Cough / history
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Whooping Cough / microbiology*
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Whooping Cough / prevention & control
Substances
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Adhesins, Bacterial
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Bacterial Outer Membrane Proteins
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Pertussis Vaccine
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Virulence Factors, Bordetella
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filamentous hemagglutinin adhesin, Bordetella pertussis
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pertactin