Chronic obstructive pulmonary disease (COPD) and cardiovascular diseases often coexist and are the predictors of severe outcomes. The purpose of literature review is analytical analysis of complex, multifactorial links between myocardial infarction and COPD. The nature and underlying mechanisms of link between the diseases are presented. It was concluded that endothelial dysfunction, chronic systemic inflammation and the system of coagulation and anticoagulation are common pathogenic mechanisms providing development of myocardial infarction in the patients with COPD.