Complete Genomic Sequence of an Australian Sindbis Virus Isolated 44 Years Ago Reveals Unique Indels in the E2 and nsP3 Proteins

Paul Pickering; John G Aaskov; Wenjun Liu

doi:10.1128/MRA.00246-19

Complete Genomic Sequence of an Australian Sindbis Virus Isolated 44 Years Ago Reveals Unique Indels in the E2 and nsP3 Proteins

Microbiol Resour Announc. 2019 May 16;8(20):e00246-19. doi: 10.1128/MRA.00246-19.

Authors

Paul Pickering¹, John G Aaskov^{1

2}, Wenjun Liu³

Affiliations

¹ Australian Defence Force Malaria and Infectious Disease Institute, Enoggera, Australia.
² Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia.
³ Australian Defence Force Malaria and Infectious Disease Institute, Enoggera, Australia Wenjun.liu@defence.gov.au.

Abstract

The complete genome sequence of a Sindbis virus (SINV) strain (SINV_AUS_1975_18953) isolated in Australia in 1975 from Culex annulirostris mosquitoes revealed unique deletions in amino acid positions 182 to 184 and 201 to 228 of the E2 envelope protein and multiple indels in the nonstructural protein 3 (nsP3).