Hepatic involvement in sarcoidosis

Ter Arkh. 2019 May 15;91(4):8-16. doi: 10.26442/00403660.2019.04.000179.

Abstract

Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Liver is frequently involved in the pathological process. Wide range of clinical manifestations can be seen: from asymptomatic lesion with normal liver function tests to cirrhosis with portal hypertension. Biopsy plays the key role in diagnosis of the hepatic sarcoidosis. It is essential for morphological diagnosis to exclude other causes of granulomatous liver disease, most often - primary biliary cholangitis. Nowadays there are no standard treatment protocols for patients with hepatic sarcoidosis.

Keywords: granulomatous liver disease; primary biliary cholangitis; sarcoidosis.

Publication types

  • Editorial

MeSH terms

  • Biopsy
  • Humans
  • Liver Cirrhosis* / etiology
  • Liver Cirrhosis, Biliary* / etiology
  • Liver Diseases* / etiology
  • Sarcoidosis* / complications