Association Between Low Serum Magnesium Level And Type 2 Diabetes Mellitus In Abbottabad

J Ayub Med Coll Abbottabad. 2019 Apr-Jun;31(2):226-229.

Abstract

Background: Magnesium serves as a cofactor for various oxidation reactions in the body and helps in glucose transport across cell membrane. Deficiency of magnesium is a common electrolyte abnormality in type 2 diabetic patients and is linked to development of various diabetic complications. This study was conducted to determine the association between low serum magnesium level and type 2 diabetes mellitus presenting at Medical B ward, BBS Hospital Abbottabad.

Methods: This descriptive study was conducted over a period of 6 months starting July 1, 2017. One hundred & eighty diagnosed diabetic patients aged at least 40 years, were included in the study. Their serum magnesium level was checked after withdrawing blood under strict aseptic conditions. Fasting & random blood glucose and the level of glycosylated haemoglobin were measured and age, gender, duration of illness were recorded on a proforma.

Results: Sixty-one patients (33.89%) had hypomagnesemia. There was no significant association between hypomagnesemia and age and sex of patients (p>0.05). However, hypomagnesemia was found to be significantly associated with the duration of diabetes mellitus among study population (p=0.02).

Conclusions: Hypomagnesemia is frequently present in patients with diabetes mellitus and it appears that its prevalence increases with the duration of diabetes mellitus.

Keywords: Serum Magnesium levels; Type 2 Diabetes Mellitus; electrolyte disturbance; HbA1C.

MeSH terms

  • Adult
  • Blood Glucose / analysis
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2* / blood
  • Diabetes Mellitus, Type 2* / epidemiology
  • Female
  • Glycated Hemoglobin / analysis
  • Humans
  • Magnesium / blood*
  • Magnesium Deficiency* / blood
  • Magnesium Deficiency* / epidemiology
  • Male
  • Pakistan / epidemiology

Substances

  • Blood Glucose
  • Glycated Hemoglobin A
  • Magnesium