Targeting the SPHK1/HIF1 Pathway to Inhibit Colorectal Cancer Stem Cells Niche

J Gastrointest Cancer. 2020 Jun;51(2):716-717. doi: 10.1007/s12029-019-00219-8.
No abstract available

Publication types

  • Editorial

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Biomarkers, Tumor / metabolism
  • Colorectal Neoplasms / drug therapy*
  • Colorectal Neoplasms / metabolism
  • Colorectal Neoplasms / pathology
  • Humans
  • Hypoxia-Inducible Factor 1, alpha Subunit / antagonists & inhibitors*
  • Molecular Targeted Therapy*
  • Neoplastic Stem Cells / drug effects*
  • Neoplastic Stem Cells / metabolism
  • Neoplastic Stem Cells / pathology
  • Phosphotransferases (Alcohol Group Acceptor) / antagonists & inhibitors*
  • Prognosis
  • Stem Cell Niche / drug effects*

Substances

  • Antineoplastic Agents
  • Biomarkers, Tumor
  • HIF1A protein, human
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Phosphotransferases (Alcohol Group Acceptor)
  • sphingosine kinase