Microwave ablation assisted by three-dimensional visualization system as local therapy for relapsed hepatoblastoma: a small pilot study

Abdom Radiol (NY). 2019 Aug;44(8):2909-2915. doi: 10.1007/s00261-019-02011-5.

Abstract

Purpose: We aimed to explore the feasibility of microwave ablation (MWA) assisted by three-dimensional visualization system for relapsed HB in children.

Methods: From August 2014 to February 2017, five patients with relapsed HB were enrolled. A total of 12 liver tumors were treated with MWA assisted by a three-dimensional visualization system. Follow-up data were obtained in all patients. The residual liver volume, local tumor progression, new intrahepatic tumors, survival outcome, and complications were analyzed.

Results: All tumors were completely ablated in a single session. The mean ablation time per tumor was 9.7 ± 8.6 min, and the median ablation/liver volume ratio was 2.37%. No local tumor progression was observed during a follow-up period of 9-39 months. All patients were still alive at the end of the follow-up. The median progression-free survival time after ablation was 9 months, and the median survival time after ablation was 12 months. No other complications were observed except for fever.

Conclusions: MWA assisted by three-dimensional visualization system appears to be a safe and feasible local treatment for recurrent HB in pediatric patients.

Keywords: Ablation techniques; Children; Hepatoblastoma; Microwave.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Catheter Ablation / methods*
  • Child
  • Child, Preschool
  • Disease Progression
  • Feasibility Studies
  • Female
  • Hepatoblastoma / diagnostic imaging*
  • Hepatoblastoma / mortality
  • Hepatoblastoma / surgery*
  • Humans
  • Imaging, Three-Dimensional*
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / mortality
  • Liver Neoplasms / surgery*
  • Magnetic Resonance Imaging*
  • Male
  • Microwaves / therapeutic use*
  • Retrospective Studies
  • Survival Rate