Phytochemical investigation of Hyoscyamus albus

Pak J Pharm Sci. 2019 Mar;32(2):661-667.

Abstract

The work presented in this paper illustrates the isolation and structure elucidation of secondary metabolites of Hyoscyamus albus. Two new natural source and three known compounds were isolated from the Hyoscyamus albus. Among the isolated compounds, grivilloside H (1) and betulaplatoside (2) were isolated for the first time while scopolamine (3), β-sitosterol (4) and stigmasterol (5) have been reported previously from the same plant. The structures of all the isolated compounds were established by using modern spectroscopic technique (UV, IR, NMR, and EI-MS) and by comparing with those available in literature.

MeSH terms

  • Glucosides / chemistry
  • Glucosides / isolation & purification
  • Glucosides / metabolism
  • Hyoscyamus / chemistry
  • Hyoscyamus / metabolism*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Phytochemicals / chemistry*
  • Phytochemicals / isolation & purification
  • Phytochemicals / metabolism
  • Plants, Medicinal / chemistry
  • Plants, Medicinal / metabolism*
  • Scopolamine / chemistry
  • Scopolamine / isolation & purification
  • Scopolamine / metabolism
  • Secondary Metabolism
  • Sitosterols / chemistry
  • Sitosterols / isolation & purification
  • Sitosterols / metabolism
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet
  • Stigmasterol / chemistry
  • Stigmasterol / isolation & purification
  • Stigmasterol / metabolism

Substances

  • Glucosides
  • Phytochemicals
  • Sitosterols
  • gamma-sitosterol
  • Stigmasterol
  • Scopolamine