Further Defining the Human Virome using NGS: Identification of Redondoviridae

Kristin Noell; Jay K Kolls

doi:10.1016/j.chom.2019.04.010

Further Defining the Human Virome using NGS: Identification of Redondoviridae

Cell Host Microbe. 2019 May 8;25(5):634-635. doi: 10.1016/j.chom.2019.04.010.

Authors

Kristin Noell¹, Jay K Kolls²

Affiliations

¹ Departments of Pediatrics & Medicine, Center for Translational Research in Infection and Inflammation, Tulane University School of Medicine, New Orleans, LA, USA.
² Departments of Pediatrics & Medicine, Center for Translational Research in Infection and Inflammation, Tulane University School of Medicine, New Orleans, LA, USA. Electronic address: jkolls1@tulane.edu.

Abstract

In this issue of Cell Host & Microbe, Abbas et al. (2019) uncover a previously undefined family of single-stranded DNA viruses, Redondoviridae, in human ororespiratory sites. The presence of Redondoviridae associates with critical illness such as respiratory failure and periodontitis, illustrating the power of metagenomics to define the human virome.

Publication types

Comment

MeSH terms

High-Throughput Nucleotide Sequencing
Humans
Lung Transplantation*
Metagenomics
Primary Graft Dysfunction*
Torque teno virus*

Grants and funding

R35 HL139930/HL/NHLBI NIH HHS/United States