Identification of a novel HLA-C allele, HLA-C*07:778, in an unrelated hematopoietic stem cell donor

HLA. 2019 Aug;94(2):161-162. doi: 10.1111/tan.13575. Epub 2019 May 26.

Authors

Alison J Gareau^{1

2}, Ahmed A Mostafa¹, Jolene Williams¹, Luz Stamm¹, Noureddine Berka^{1

2}

Affiliations

¹ Histocompatibility and Immunogenetics Laboratory, Alberta Public Laboratories, Calgary, Alberta, Canada.
² Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada.

PMID: 31069965
DOI: 10.1111/tan.13575

Abstract

HLA-C*07:778 differs from HLA-C*07:01:01:01 by a single nonsynonymous nucleotide substitution at codon 263 (CAC→CAG).

Keywords: HLA-C; next-generation sequencing; novel allele.

© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles*
Exons / genetics
HLA-C Antigens / genetics*
Hematopoietic Stem Cells / metabolism*
Histocompatibility Testing
Humans
Unrelated Donors*

Substances

HLA-C Antigens