Determining a cutoff score for the family burden interview schedule using three statistical methods

BMC Med Res Methodol. 2019 May 8;19(1):93. doi: 10.1186/s12874-019-0734-8.

Abstract

Background: While it is widely acknowledged that family burden can be ameliorated with effective psycho-social interventions, how to measure family burden and define a valid cutoff to identify family caregivers in need of such interventions remains a key question. The purpose of the present study was to determine a statistically valid cutoff score for the Family Burden Interview Schedule (FBIS), using the cutoff scores of the Patient Health Questionnaire (PHQ-9) and the Generalized Anxiety Disorder Scale (GAD-7) as the reference.

Methods: The FBIS, PHQ-9, and GAD-7 were administered to a representative community sample of 327 family caregivers of schizophrenia patients. A FBIS cutoff score was determined using three different statistical methods: tree-based modeling, K-means clustering technique and linear regression. Contingency analysis was conducted to compare the FBIS cutoff with depression and anxiety scale scores.

Results: Findings proposed a cutoff score of 23 for the FBIS, with sensitivity being 76% for PHQ-9 and 74% for GAD-7, specificity being 68% for PHQ-9 and 67% for GAD-7.

Conclusion: This cutoff score would enable health care providers to assess family caregivers at risk and provide necessary interventions to improve their quality of life.

Keywords: Cutoff; Family burden interview schedule (FBIS); K-means clustering technique; Linear regression; Sensitivity; Specificity; Tree-based modeling.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anxiety Disorders / diagnosis
  • Caregivers / psychology*
  • China
  • Female
  • Health Status Indicators*
  • Health Status*
  • Humans
  • Male
  • Middle Aged
  • Psychometrics / methods*
  • Quality of Life / psychology
  • Schizophrenia / therapy