The effectiveness of RENAL nephrometry score in ablated renal tumors via radiofrequency ablation or cryoablation

Turk J Med Sci. 2019 Jun 18;49(3):761-768. doi: 10.3906/sag-1811-131.

Abstract

Background/aim: This study aimed to evaluate the clinical efficacy of radiofrequency ablation (RFA) and cryotherapy and to scrutinize the therapeutic success of the RENAL (radius, exophytic/endophytic, nearness to collecting system, anterior/posterior, and location) nephrometry score in terms of possible complications and the predictive status of oncological results.

Materials and methods: Forty-five patients with biopsy-proven renal cell carcinomas (32 males, 13 females) treated with RFA and cryotherapy were included. Patients were 22–90 years old (average: 59.2 years). Statistical analyses were performed using SPSS for Windows.

Results: A total of 79 lesions with dimensions varying between 0.9 and 4.5 cm (average: 2.2 cm) were ablated. Complete ablation was achieved for 72 (91.1%) lesions. Six repeat RFA sessions were applied for 4 (5%) lesions with residue/recurrence. The average RENAL nephrometry scores of lesions that underwent complete ablation and those that developed residue/recurrence were 6.3 and 7.7, respectively. The average recurrence-free survival time was 34.8 months (range: 3–55 months), while it was 44.6 months (range: 6–55 months) for cryotherapy and 28.6 months (range: 3–50 months) for RFA.

Conclusion: Ablative therapies are minimally invasive and effective methods for treating small renal tumors. RENAL nephrometry scoring is a valuable system for standardizing renal tumors and evaluating the success of ablative therapies, possible complications, and oncological results.

Keywords: Radiofrequency ablation; cryotherapy; RENAL nephrometry score.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cryosurgery / statistics & numerical data*
  • Female
  • Humans
  • Kidney Function Tests*
  • Kidney Neoplasms* / epidemiology
  • Kidney Neoplasms* / physiopathology
  • Kidney Neoplasms* / surgery
  • Male
  • Middle Aged
  • Radiofrequency Ablation / statistics & numerical data*
  • Young Adult