Endovascular Treatment of Post-thrombotic Venous Ilio-Femoral Occlusions: Prognostic Value of Venous Lesions Caudal to the Common Femoral Vein

Cardiovasc Intervent Radiol. 2019 Aug;42(8):1117-1127. doi: 10.1007/s00270-019-02214-9. Epub 2019 May 6.

Abstract

Objectives: To propose a scale of severity for post-thrombotic venous lesions (PTVLs) after ilio-femoral deep venous thrombosis and to compare the grade with the results of endovascular treatment of ilio-femoral PTVLs.

Methods: In this retrospective monocentric observational study, we included 95 patients treated for ilio-femoral PTVLs. We proposed a four-grade scale evaluating the severity of PTVLS caudal to the common femoral vein based on CT phlebography and per-operative phlebography. For most patients, venous patency was assessed with color duplex ultrasonography and the clinical efficacy of the intervention using the Villalta and CIVIQ scores.

Results: Recanalization was successful in 100% of patients with a morbidity rate of 4%. After a mean follow-up of 21 months, the overall primary patency was 75%, the assisted primary patency 82%, and the secondary patency 93%. Secondary patency was 100% for grade 0-1, 90% for grade 2, and 63% for grade 3 (p < 0.002). There was no correlation between the extension of stenting caudally of the common femoral vein and venous patency. The mean improvements in the Villalta and CIVIQ-20 scores were, respectively, 4.6 (p < 0.0001) and 18 (p < 0.0001); scores were not correlated with the grade of PTVLs in the thigh.

Conclusion: Venous patency after endovascular treatment of ilio-femoral PTVLs was strongly linked to the severity of PTVLs caudal to the common femoral vein but not to the extent of stenting.

Keywords: Deep venous thrombosis; Iliac vein; Inferior vena cava; Post-thrombotic syndrome; Stent.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Arterial Occlusive Diseases / complications
  • Arterial Occlusive Diseases / diagnostic imaging
  • Arterial Occlusive Diseases / surgery*
  • Endovascular Procedures / methods*
  • Female
  • Femoral Vein / diagnostic imaging
  • Femoral Vein / surgery*
  • Humans
  • Iliac Vein / diagnostic imaging
  • Iliac Vein / surgery*
  • Male
  • Middle Aged
  • Postthrombotic Syndrome / complications
  • Postthrombotic Syndrome / surgery*
  • Prognosis
  • Retrospective Studies
  • Treatment Outcome
  • Ultrasonography, Doppler, Color
  • Young Adult