Data on genotype frequency for SNPs associated to age of smoking onset and successful smoking cessation treatment

Gloria Pérez-Rubio; Luis Alberto López-Flores; Alejandra Ramírez-Venegas; Raúl H Sansores; Ramcés Falfán-Valencia

doi:10.1016/j.dib.2019.103893

Data on genotype frequency for SNPs associated to age of smoking onset and successful smoking cessation treatment

Data Brief. 2019 Apr 17:24:103893. doi: 10.1016/j.dib.2019.103893. eCollection 2019 Jun.

Authors

Gloria Pérez-Rubio¹, Luis Alberto López-Flores¹, Alejandra Ramírez-Venegas², Raúl H Sansores³, Ramcés Falfán-Valencia¹

Affiliations

¹ HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City, 14080, Mexico.
² Departamento de Investigación en Tabaquismo y EPOC, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, México City, Mexico.
³ Clínica de Enfermedades Respiratorias, Fundación Médica Sur, Mexico City, 14080, Mexico.

Abstract

This article contains data on the allele and genotype frequency for single nucleotide polymorphisms (SNPs) in candidate genes CHRNA5 (rs16969968, rs17408276, rs680244) CHRNA3 (rs6495307, rs12914385) NRXN1 (rs10865246, rs1882296, rs985919) and HTR2A (rs6311, rs6313) previously evaluated as genetic risk variants for cigarette smoking at an early age and relapse to smoking cessation treatment Pérez-Rubio et al., 2018. These SNPs were selected due to previous associations in other populations, including Mexican Mestizos. Smokers were classified according to the age at onset, cigarettes per day, nicotine dependence, COPD status and therapy received.