Cladosporium sphaerospermum causing brain abscess, a saprophyte turning pathogen: Case and review of published reports

N Batra; H Kaur; S Mohindra; S Singh; A S Shamanth; S M Rudramurthy

doi:10.1016/j.mycmed.2019.04.005

Cladosporium sphaerospermum causing brain abscess, a saprophyte turning pathogen: Case and review of published reports

J Mycol Med. 2019 Jun;29(2):180-184. doi: 10.1016/j.mycmed.2019.04.005. Epub 2019 May 2.

Authors

N Batra¹, H Kaur², S Mohindra³, S Singh¹, A S Shamanth¹, S M Rudramurthy¹

Affiliations

¹ Department of Medical Microbiology, Post graduate institute of medical education and research, Chandigarh, India.
² Department of Medical Microbiology, Post graduate institute of medical education and research, Chandigarh, India. Electronic address: drharsimranpgi@gmail.com.
³ Department of Neurosurgery, Post graduate institute of medical education and research, Chandigarh, India.

PMID: 31056403
DOI: 10.1016/j.mycmed.2019.04.005

Abstract

Emergence of saprophytic fungi thriving in dead plant material and soil as opportunistic human pathogens is of great concern. Cladosporium species are environmental saprophytes reported to cause various superficial and invasive fungal infections worldwide. C. sphaerospermum, a predominantly indoor fungus has been reported from cases of meningitis, subcutaneous and pulmonary fungal infections in the past. Herein we report the first case of cerebral abscess due to C. sphaerospermum in an immunocompetent host who was successfully managed by combined medical and surgical therapy.

Keywords: Brain abscess; Cladosporium sphaerospermum; Immunocompetent.

Publication types

Case Reports
Review

MeSH terms

Adult
Antifungal Agents / pharmacology
Brain / diagnostic imaging
Brain Abscess / microbiology*
Brain Abscess / surgery
Cladosporium / isolation & purification*
Cladosporium / pathogenicity*
Humans
Immunocompetence
Magnetic Resonance Imaging
Male
Mycoses / diagnosis*
Mycoses / drug therapy
Treatment Outcome

Substances

Antifungal Agents