An effective scheme to enhance the yield of high-order harmonic generation originated from spatially inhomogeneous field through the interaction between few-cycle chirped laser pulses and a nano-tip structure is demonstrated. The conversion efficiency of harmonics from chirped laser pulses was significantly improved by nearly three more orders of magnitude than that of chirp-free pulses, and the cutoff energy of the corresponding harmonics was dramatically enhanced. By superimposing a series of properly selected orders of harmonics, isolated attosecond pulses of high intensity can be obtained. Furthermore, we compared the effects of different types of chirps on harmonics.