Abstract
Histoplasmosis is a rare disease in nonendemic areas. We report a case of a 23-year-old male patient who presented with fever of unknown origin, cytopenias, organomegaly, and allograft dysfunction 4 months after renal transplant with father as donor. Bone marrow examination showed intracellular budding yeast cells, which was confirmed as histoplasmosis by culture of bone marrow biopsy sample. The patient was treated with intravenous liposomal amphotericin and responded well.
MeSH terms
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Administration, Intravenous
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Amphotericin B / administration & dosage
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Antifungal Agents / administration & dosage
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Biomarkers / blood
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Fever of Unknown Origin / blood
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Fever of Unknown Origin / diagnosis
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Fever of Unknown Origin / microbiology*
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Histoplasma / drug effects
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Histoplasma / isolation & purification*
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Histoplasmosis / blood
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Histoplasmosis / diagnosis
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Histoplasmosis / drug therapy
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Histoplasmosis / microbiology*
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Humans
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Kidney Transplantation / adverse effects*
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L-Lactate Dehydrogenase / blood*
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Male
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Predictive Value of Tests
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Treatment Outcome
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Young Adult
Substances
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Antifungal Agents
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Biomarkers
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liposomal amphotericin B
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Amphotericin B
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L-Lactate Dehydrogenase