Preventive effect of exercise training on diabetic kidney disease in ovariectomized rats with type 1 diabetes

Exp Biol Med (Maywood). 2019 Jun;244(9):758-769. doi: 10.1177/1535370219843830. Epub 2019 May 1.

Abstract

To date, no studies have been found evaluating the effects of physical exercise on renal function and structure changes in ovariectomized rats with type 1 diabetes. Therefore, this work emerges with an important tool for strengthening and expanding innovative research on exercise with potential for the prevention of renal diseases in ovariectomized diabetic rats, and future development of studies that seek to increase scientific knowledge about the beneficial effects of physical exercise on renal diseases in humans.

Keywords: Exercise training; diabetic kidney disease; ovariectomy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood Glucose / analysis
  • Creatinine / blood
  • Diabetes Mellitus, Experimental / complications*
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetic Nephropathies / prevention & control*
  • Estradiol / blood
  • Exercise Therapy
  • Female
  • Ovariectomy* / adverse effects
  • Physical Conditioning, Animal*
  • Rats
  • Rats, Wistar

Substances

  • Blood Glucose
  • Estradiol
  • Creatinine