Castleman Disease Masquerading as the Posterior Mediastinal Mass on 18F-Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography

Vanshika Gupta; Ritu Verma; Dharmender Malik; Ethel Shangne Belho; Sunila Jain; Harsh Mahajan

doi:10.4103/ijnm.IJNM_1_19

Castleman Disease Masquerading as the Posterior Mediastinal Mass on ¹⁸F-Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography

Indian J Nucl Med. 2019 Apr-Jun;34(2):171-172. doi: 10.4103/ijnm.IJNM_1_19.

Authors

Vanshika Gupta¹, Ritu Verma¹, Dharmender Malik¹, Ethel Shangne Belho¹, Sunila Jain², Harsh Mahajan¹

Affiliations

¹ Department of Nuclear Medicine and PET/CT, Centre for Advanced Research in Imaging, Neuroscience and Genomics, Sir Ganga Ram Hospital, New Delhi, India.
² Department of Pathology, Sir Ganga Ram Hospital, New Delhi, India.

Abstract

A 28-year-old female presented with an incidentally detected mediastinal mass, found on routine chest X-ray. ¹⁸F-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) was advised to plan course of further management. FDG-PET/CT findings were suggestive of an FDG-avid soft-tissue mass in the left posterior mediastinum in paravertebral location with left pleural effusion. Overall, PET/CT scan findings favored the possibility of a nerve sheath tumor. However, histopathology along with immunohistochemistry confirmed the diagnosis of Castleman disease.

Keywords: Castleman disease; fluorodeoxyglucose-positron emission tomography/computed tomography; lymphoproliferative disorder; posterior mediastinal mass.