GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells

Haematologica. 2019 May;104(5):e229. doi: 10.3324/haematol.2019.220533.

Beibei Zhang^{1

2}, Pilar Ayuda-Durán^{1

2}, Laure Piechaczyk^{1

2

3}, Yngvar Fløisand^{1

2

4}, Mireia Mayoral Safont⁵, Ida Tveit Karlsen⁵, Zina Fandalyuk⁵, Dagim Tadele^{1

2

3}, Pepijn van Mierlo¹, Alexander D Rowe⁶, Joseph M Robertson^{1

2}, Bjørn Tore Gjertsen^{4

7}, Emmet McCormack^{4

7}, Jorrit M Enserink^{8

2

9}

¹ Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Montebello.
² Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, Montebello.
³ Institute of Clinical Medicine, University of Oslo.
⁴ Department of Hematology, Oslo University Hospital, Rikshospitalet, Oslo.
⁵ Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen.
⁶ Norwegian National Unit for Newborn Screening, Woman and Children's Division, Oslo University Hospital, Rikshospitalet.
⁷ Hematology Section, Department of Internal Medicine, Haukeland University Hospital, Bergen.
⁸ Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Montebello jorrit.enserink@rr-research.no.
⁹ Section for Biochemistry and Molecular Biology, The Department of Biosciences, Faculty of Mathematics and Natural Sciences, University of Oslo, Norway.

No abstract available

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