The efficacy of a bioglass (45S5) paste temporary filling used to remineralize enamel surfaces prior to bonding procedures

Abstract

Objectives: The efficacy of using a 45S5 Bioglass paste as a remineralizing temporary filling material was compared to fluoride gel (1.23% acidulated-phosphate-fluoride, Gelato Gel, NJ, USA) applied for 24 h and for 4 min and to a temporary filling material (Caviton; GC, Tokyo, Japan).

Methods: 66 extracted human premolars were used. All specimens were sectioned mesio-distally. All specimens were challenged by a demineralization solution (pH4.5) for 4 days. The specimens were divided into 4 groups: (Bioglass), (Fluoride 4-minutes), (Fluoride 24-Hours), and (Temp) (n = 33). 10 specimens were examined by TMR (Transversal Microradiography)to test remineralization capacity of each agent. 8 specimens were assigned to determine the acid resistance of a bonded resin-enamel interface after the various treatment methods. 15 samples were assigned to determine the effect of each agent on the shear bond strength of a single bottle self-etch adhesive system. One way ANOVA was used to compare the obtained results (p < 0.05).

Results: Specimens treated with 45S5 bioglass showed statistically significant reductions in (delta z) values when compared to the other three groups (p < 0.05). Treatment of demineralized enamel by fluoride prior to bonding significantly decreased shear bond strength values, however 45S5 bioglass treatment did not affect the shear bond strength of adhesive system to enamel (p < 0.05). The acid-resistance of the interface between resin-enamel was significantly improved when fluoride or bioglass were applied onto the enamel surface prior to demineralization.

Conclusions: 45S5 bioglass paste has high potential to be used as a remineralizing temporary filling material.

Keywords: 45S5; Bioglass; Remineralization; Trans-micro radiography.